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Management of the behavioral and psychological symptoms of dementia (BPSD) is a hot topic because these commonly seen symptoms in persons with dementia are quite difficult to manage.As highlighted in the comments by Xiao[1],the administration of antipsychotics is controversial because the use of antipsychotic medications in persons with dementia is associated with increased mortality,increased risk of stroke and worsened cognitive function[2,3].Xiao recommends that more long-term follow-up studies on the management of the BPSD be conducted to give clinicians better guidance on the treatment of this complex condition.This recommendation is particularly pertinent for Chinese populations.Two studies from Hong Kong showed that patients with the BPSD who were treated with antipsychotic medications did not have an increased risk of cerebrovascular accidents[4]or mortality[5].Clearly,more studies should be conducted in populations of different ethnicity to confirm or disprove the presumed risks of antipsychotic medications in patients with dementia.