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目的探讨应用二维应变(2DS)测定左室心内膜下、中层和心外膜下心肌收缩期纵向峰值应变(SSL)评价无左心室重构高血压患者左室收缩功能的应用价值。方法选取40例无左室重构的高血压患者(HT组)和50例健康志愿者(对照组),应用2DS获取所有患者心尖位切面心内膜下、中层和心外膜下心肌SSL及各切面整体SSL。结果对照组及HT组患者心肌各层SSL均保持梯度特征,即心内膜下心肌>中层心肌>心外膜下心肌;与对照组比较,HT组心内膜下心肌SSL减低有统计学意义(P<0.05),中层心肌和心外膜下心肌SSL减低无统计学意义(P>0.05);对照组和HT组各切面整体SSL无统计学差异(P>0.05)。结论 2DS可评价无左心室重构高血压患者左室心肌分层应变,为判断高血压心脏病的心肌受累程度提供一种新方法。
Objective To investigate the value of 2-dimensional strain (2DS) in determining left ventricular systolic left-ventricular systolic function in patients with left ventricular remodeling hypertension (LVH). Methods 40 hypertensive patients without left ventricular remodeling (HT group) and 50 healthy volunteers (control group) were enrolled in this study. All patients underwent apheresis and allo-epicardial subendocardial SSL with 2DS All aspects of the overall SSL. Results In the control group and the HT group, the SSL of each layer of the myocardium maintained the gradient characteristic, that is, the subendocardium> the middle myocardium> the epicardial myocardium. Compared with the control group, the SSL in the subendocardial myocardium in the HT group was significantly decreased (P <0.05). There was no significant difference in SSL between middle myocardium and epicardial myocardium (P> 0.05). There was no significant difference in SSL between control group and HT group (P> 0.05). Conclusion 2DS can assess left ventricular myocardial stratification in hypertensive patients without left ventricular remodeling, and provide a new method for judging myocardial involvement in hypertensive heart disease.