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目的:对幽门螺旋杆菌(Hp)胃溃疡采用四联疗法进行治疗的临床效果进行分析研究。方法:将我院收治的幽门螺杆菌胃溃疡患者随机分为两组,一组接受三联疗法治疗,一组接受四联疗法治疗,比较两组患者的临床治疗效果。结果:接受四联疗法的患者组,其Hp清除率高于接受三联疗法的患者组,但只是差异并不明显;接受四联疗法的患者组其临床治疗有效率明显高于接受三联疗法的患者组,其不良反应发生率明显低于三联疗法患者组,p<0.05。结论:四联疗法能够有效清除患者体内幽门螺杆菌,提高胃溃疡临床治疗效果,且不良反应较少,可以在临床中推广应用。
Objective: To analyze the clinical effect of quadruple therapy on Helicobacter pylori (Hp) gastric ulcer. Methods: Patients with Helicobacter pylori gastric ulcer admitted to our hospital were randomly divided into two groups. One group received triple therapy and the other received quadruple therapy. The clinical effects of two groups were compared. Results: Patients in the quadruple therapy group had higher Hp clearance rates than those who received triple therapy, but only with no significant difference; patients treated with quadruple therapy had significantly better clinical outcomes than those treated with triple therapy Group, the incidence of adverse reactions was significantly lower than triple therapy patients, p <0.05. Conclusion: The quadruple therapy can effectively remove Helicobacter pylori in patients and improve the clinical curative effect of gastric ulcer with less adverse reactions, which can be widely applied in clinic.