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目的:探讨不同阶段妊娠高血压综合征(妊高征)患者血清肾功能指标变化的临床意义。方法:回顾性分析107例妊高征患者主要的肾功能指标,并与80例正常妊娠无合并症的孕妇作比较。结果:妊高征患者血清尿素氮、肌酐均高于对照组,尿酸则显著高于对照组,均有统计学意义(P<0.05~0.001),三者升高程度与病情正相关。结论:妊高征患者肾功能标较正常妊娠妇女有明显变化,以尿酸水平的变化最为明显,测定这些指标对妊高征的诊断、病情监测有一定的临床意义。
Objective: To investigate the clinical significance of serum renal function indexes in patients with pregnancy induced hypertension (PIH) in different stages. Methods: The main indexes of renal function in 107 patients with PIH were retrospectively analyzed and compared with 80 pregnant women without complications of normal pregnancy. Results: The levels of serum urea nitrogen and creatinine in patients with PIH were significantly higher than those in the control group, and uric acid was significantly higher than that in the control group (P <0.05 ~ 0.001). Conclusion: The index of renal function in patients with PIH is significantly different from that of normal pregnant women, and the change of uric acid level is the most obvious. The determination of these indexes has certain clinical significance for diagnosis and condition monitoring of PIH.