Studies on the Synthesis of Penazetidine A, an Alkaloid Inhibitor of Protein Kinase C

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：yuezhiyaodao

【摘要】

：

A convergent asymmetric synthesis of (2S, 3R, 4S, 12’R)-3-hydroxy-2-hydroxymethyl- 4-(12’ -methyloctadecyl)-N-(p-tolylsulfonyl)-azetidine, a key precursor of

【作者】

：

Zhi Ming LI Bing WANG Feng Gan

【机构】

：

Department of Chemistry, Fudan University, Shanghai 200433;Shanghai Institute of Organic Chemistry,

【出处】

：

中国化学快报（英文版）

【发表日期】

：

2004年2期

【关键词】

：

Penazetidine A alkaloid azetidine Wittig reaction

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A convergent asymmetric synthesis of (2S, 3R, 4S, 12’R)-3-hydroxy-2-hydroxymethyl- 4-(12’ -methyloctadecyl)-N-(p-tolylsulfonyl)-azetidine, a key precursor of penazetidine A, has been achieved by starting from divinylcarbinol.

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Studies on the Synthesis of Penazetidine A, an Alkaloid Inhibitor of Protein Kinase C

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