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对63例膀胱癌和13例正常膀胱粘膜上皮进行X染色质(X chromatin,通常以Barrbody表示)出现率(BBF)进行观测。结果:BBF在正常膀胱粘膜上皮与Ⅱ、Ⅲ级膀胱癌间差异有极显著性,在有无肿瘤转移复发间的差异有高度显著性;在5年生存与5年死亡组间差异亦有极显著性。提示BBF愈低,肿瘤的分化程度愈差,生物学行为愈恶劣(BBF在45％以上无转移复发,30％以下出现转移复发)。BBF降到20％为危险信号(BBF<20％的病例5年内均死于膀胱癌,BBF>34％的病例5年生存率为100％)。
Sixty-three cases of bladder cancer and 13 cases of normal bladder mucosal epithelium were observed for X-chromatin (usually Barrbody) incidence (BBF). Results: There was a significant difference in the expression of BBF between normal bladder mucosa epithelium and grade ¢ ò and grade ¢ ó bladder cancer, with significant difference in the presence or absence of tumor metastasis and recurrence. There was also a significant difference between 5-year survival and 5-year death Significance. Prompt BBF lower, the worse the degree of tumor differentiation, the worse the biological behavior (more than 45% of BBF recurrence without metastasis, recurrence of metastasis below 30%). BBF dropped to 20% of the risk signal (BBF <20% of cases die of bladder cancer in 5 years, BBF> 34% of cases 5-year survival rate of 100%).