目前医学微生物学经常遇到的困难是病原微生物与近似的腐生菌之间界线不易确定。特别是条件致病菌,由于在医疗中化学治疗剂,尤其是广谱抗生素的应用,引起它们生态学的改变,使其病理学意义在急剧地增加。葡萄球菌就是这样一类微生物。这些情况激起了研究者们对萄萄球菌属进行更深入的研究。发现真正腐生性不致病的葡萄球菌是不存在的,凝固酶阴性的葡萄球菌是一群性质很不相同的微生物。在研究过程中,生物化学和分子生物学的新成就如 Current medical microbiology often encountered difficulties is the pathogenic microorganisms and similar boundaries between the saprophytic easily determined. Especially opportunistic pathogens, cause their ecological changes due to the application of chemotherapeutic agents in medical treatment, especially broad-spectrum antibiotics, causing their pathological significance to increase dramatically. Staphylococcus is one type of microorganism. These circumstances have inspired researchers to conduct a more in-depth study of the genus Staphylococcus. Found that the real saprophytic non-pathogenic Staphylococcus is non-existent, coagulase-negative staphylococcus is a group of very different nature of the micro-organisms. New achievements in biochemistry and molecular biology in the research process