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用放射免疫分析技术测定22名接受蓝光照射的黄疸早产婴(光疗组)和32名生理性黄疸早产婴(对照组)生后5周内血清促性腺激素水平.结果显示:对照组血清卵泡刺激素(FSH)第1周为低水平,无性别差异;第2周开始明显上升,女婴的水平显著高于男婴,高水平持续较久.血清黄体生成素(LH)生后头两周为低水平,以后显著上升;女婴始终低于男婴.光疗组男女婴血清FSH 和LH水平均明显下降,女婴的下降幅度大于男婴,LH 在下降之后有回升.本研究提示:(1)生理性黄疸早产婴血清促性腺激素水平与性别、日龄相关.(2)光照对早产婴垂体-性腺轴的功能有影响,并可能与性别、日龄及光波波长相关.
Radioimmunoassay was used to determine the level of serum gonadotropin in 22 neonates with preterm neonates with jaundice (phototherapy) and 32 preterm infants with physiological jaundice (control) who received blue light irradiation.The results showed that serum follicle stimulation The level of FSH in the first week was low and there was no gender difference. The level of FSH was significantly higher in the second week than that of the male infant and the high level continued for a long time. The first two weeks after the birth of serum LH, The level of FSH and LH in male and female babies in phototherapy group were significantly lower than those in male babies and LH was decreased after LH dropped.The study suggests that The serum gonadotrophin level in preterm infants with physiological jaundice is related to sex and age. (2) The effects of light on the function of the pituitary-gonad axis in preterm infants may be related to gender, age and light wavelength.