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本文报道应用激光多普勒微循环流速测定仪,观察丹参注射液对狗肠系膜微循环的影响,微循环流速及管径(14～20μ)由激光多普勒效应测定。在19条狗中,注射丹参前,后5′、10′、15′及20′,测定相应流速为0.426±0.02;0.492±0.025;0.553±0.025;0.526±0.04及0.508±0.04mm/sec、(5′,10′p<0.001;15′p<0.005;20′p<0.05);在11条狗中,以银黄注射液为对照,结果用药前后相比,无显著差异(p>0.05)。丹参及银黄注射液对心电图、心率及血压均无影响。认为丹参注射液有短期增快微循环血流作用。
This article reports the use of laser Doppler microcirculation flow rate instrument to observe the effects of Danshen injection on dog mesenteric microcirculation, microcirculation flow rate and diameter (14 ~ 20μ) measured by laser Doppler effect. In 19 dogs, before and after the injection of Salvia miltiorrhiza, 5′, 10′, 15′ and 20′, the corresponding flow rates were determined to be 0.426±0.02; 0.492±0.025; 0.553±0.025; 0.526±0.04 and 0.508±0.04mm/sec. (5′,10′p<0.001;15′p<0.005;20′p<0.05); In 11 dogs, Yinhuang injection was used as a control, and the results were not significantly different before and after treatment (p>0.05). ). Danshen and Yinhuang injection had no effect on ECG, heart rate and blood pressure. It is believed that Danshen injection has a short-term increase in microcirculatory blood flow.