论文部分内容阅读
抗蛙皮素（BBS）是哺乳动物胃泌素释放肽（GRP）的十四肽同类物，广泛分布于呼吸道、中枢神经系统及胃肠道内。BBS与特异性GRP受体（GRP－R）结合，以细胞内钙离子为第二信使，活化多种核转录因子。不仅刺激胃肠激素的分泌和肠道正常粘膜组织的生长，而且作为一种促有丝分裂原?
Anti-boehtemerin (BBS) is a tetrameric peptide homolog of mammalian gastrin-releasing peptide (GRP) and is widely distributed in the respiratory tract, central nervous system and gastrointestinal tract. BBS binds to specific GRP receptors (GRP-R) and activates various nuclear transcription factors with intracellular calcium ion as the second messenger. Not only stimulates the secretion of gastrointestinal hormones and the growth of normal mucosal tissue in the intestine, but also acts as a mitogen.