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目的：研究病理Ⅰ、Ⅱ级，Ｘ线表现为ＣａｍｐａｎａｃｃｉⅡ、Ⅲ期的邻膝关节骨巨细胞瘤的治疗。方法：从１９７８～１９９３年住院治疗的骨巨细胞瘤１０３例中，选择肿瘤部位、Ｘ线分期、病理分级及随访时间相仿的病损内处置（刮除、液氮冷冻并自体或异体植骨、或骨水泥填充）患者４１例（３例有病理性骨折）；整块切除后用异体半关节移植３０例（２例有病理性骨折）进行回顾性分析。结果：显示两组间局部复发率无统计学差异，而病损内处置的术后并发症，再手术率及肢体远期功能评分均明显好于整块切除组。结论：有效的病损内处置仍应作为此类邻膝关节骨巨细胞瘤的首选治疗方法，即使诊断时伴有病理性骨折者亦然。
Objective: To study pathological grades I and II, X-ray findings of Campanacci II, III treatment of giant cell tumors adjacent to the knee. Methods: Among the 103 cases of giant cell tumor of bone that were hospitalized from 1978 to 1993, intralesional treatment (scrape, liquid nitrogen freezing, and autogenous or allogeneic bone grafting) was selected to treat the tumor site, X-ray staging, pathological grade, and follow-up time. 41 patients (3 cases had pathological fractures) were treated with bone cement, and 30 cases (2 pathological fractures) of allografts were retrospectively analyzed. Results: There was no statistical difference in the local recurrence rate between the two groups. The postoperative complications of intralesional treatment, reoperation rate and long-term limb functional scores were all significantly better than those of the en bloc resection group. CONCLUSIONS: Effective intralesional treatment should still be used as the first choice for the treatment of this type of adjacent giant cell tumor of the knee, even if it is diagnosed with a pathologic fracture.