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本文以~3H一组氨酸掺入的HRBT法,检测针灸组和对照组共46例Ⅰ型变态反应患者的组织胺释放率,藉以探讨针灸抗Ⅰ型变态反应的机理。结果表明:针灸对粉尘螨HRBT释放有较明显抑制,两组治疗后阳性率侧数卡方检验X~2=6.05,P<0.05;蟑螂HRBT释放率在哮喘症中下降较明显,针灸前后自身对照例数卡方检验X~2=6.53,P<0.05;HRBT与HBDT两指标之间的相关分析表明,治疗前后均密切相关。提示针灸作用影响到介质释放过程,对介质释放可能有重新调控作用。
In this study, the histamine release rate in 46 patients with type I allergic reactions in acupuncture group and control group was detected by HRBT method with ~3H-histidine incorporation to investigate the mechanism of acupuncture and moxibustion on type I allergy. The results showed that acupuncture and moxibustion significantly inhibited the release of HRBT from D. farinae, and the rate of positive side of the two groups after treatment showed a positive chi-square test (X~2=6.05, P<0.05). The release rate of 蟑螂HRBT was significantly decreased in asthmatic patients. The number of chi square test in the control group was X~2=6.53, P<0.05. The correlation analysis between HRBT and HBDT showed that both were closely related before and after treatment. It is suggested that acupuncture affects the release of media and may have a re-regulatory effect on media release.