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目的了解本地区围产儿出生缺陷发生状况和影响因素,探索预防控制措施,减少本地区出生缺陷发生率。方法回顾性分析2011年淄博市出生缺陷监测资料。结果 2011年全市出生缺陷发生率为7.84‰,产妇年龄<20岁和>35岁出生缺陷明显高于其他年龄组,需重点防范;出生缺陷发生无性别和城乡差异;前五种围产儿出生缺陷为先天性心脏病、多指(趾)、唇裂合并腭裂、先天性脑积水、尿道下裂,占总出生缺陷发生的44.6%。结论针对出生缺陷重点探索致畸因素,要实施有效的预防措施,加强孕前保健工作;不断提高产前筛查和产前诊断水平;逐步建立出生缺陷儿跟踪治疗网络;加强对出生缺陷监测工作的数据质量控制工作,以逐步降低出生缺陷发生率,提高存活出生缺陷儿的生存质量。
Objective To understand the occurrence and influencing factors of birth defects in perinatal infants in this area and explore preventive and control measures to reduce the incidence of birth defects in this area. Methods A retrospective analysis of 2011 Zibo birth defects monitoring data. Results The incidence of birth defects in the city in 2011 was 7.84 ‰. The birth defects in males <20 years and 35 years old were significantly higher than those in other age groups, and the prevention of birth defects was most important. There were no gender differences and urban-rural differences in birth defects. Birth defects in the first five cases For congenital heart disease, multiple fingers (toes), cleft lip cleft palate, congenital hydrocephalus, hypospadias, accounting for 44.6% of the total birth defects. Conclusion To explore the causes of teratogenicity in the light of birth defects, we must implement effective preventive measures to strengthen pre-pregnancy health care; continue to increase the level of prenatal screening and prenatal diagnosis; gradually establish a tracking network for birth defects; and strengthen the monitoring of birth defects Data quality control work to gradually reduce the incidence of birth defects and improve the survival of surviving children with birth defects quality.