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本文作者收集了近十余年来41组总病例数7415人的抗生素使用的资料,其中未预防性使用抗生素者3540人,使用预防性抗生素3875人。于手术前开始使用了预防性抗生素者,其外科感染发病率的临床双盲对照结果明显较未预防性使用抗主素者为低(见表一)。
The authors collected information on the use of antibiotics in 41 groups with a total of 7415 patients in the past 10 years, of which 3540 were non-prophylactic antibiotics and 3875 were prophylactic antibiotics. Pre-operative prophylaxis with prophylactic antibiotics resulted in a significantly lower rate of clinical infection compared with non-prophylactic use (Table 1).