论文部分内容阅读
目的探讨临床药师干预在围术期患者预防用抗菌药物中的指导作用。方法选取广丰区人民医院胸心外科2016年8月—2017年3月收治的手术患者120例,根据随机数字表法分为对照组和观察组,各60例。对照组患者的临床药师于围术期未给予任何干预,观察组患者的临床药师于围术期给予相关干预。比较两组患者用药时间、住院时间、抗菌药物费用及住院总费用,观察患者抗菌药物合理性使用情况(适应证、合理用药时间、合理给药途径、合理用药剂量、未联合用药、术前合理给药时间)。结果观察组患者用药时间、住院时间短于对照组,抗菌药物费用、住院总费用低于对照组(P<0.05)。观察组患者适应证、合理用药时间、合理给药途径、合理用药剂量、未联合用药、术前合理给药时间者所占比例高于对照组(P<0.05)。结论临床药师在胸外科围术期患者预防用抗菌药物中的作用明显,可有效提高抗菌药物合理使用率,缓解患者的经济负担,缩短住院时间,促使疾病快速恢复。
Objective To investigate the clinical pharmacist intervention in perioperative prevention of antimicrobial agents in the guidance. Methods A total of 120 surgical patients admitted from August 2016 to March 2017 in the Department of Thoracic and Cardiac Surgery, People’s Hospital of Guangfeng District were divided into control group and observation group according to the random number table. The clinical pharmacists in the control group did not give any intervention during the perioperative period, and the clinical pharmacists in the observation group were given perioperative interventions. The duration of medication, length of hospital stay, costs of antimicrobial drugs and total cost of hospitalization were compared between two groups to observe the rational use of antimicrobial agents in patients (indications, reasonable medication time, reasonable dosage, reasonable dosage, no combination therapy, reasonable preoperative Dosing time). Results The observation group had shorter medication duration and hospitalization time than the control group. The cost of antimicrobial drugs and hospitalization was lower than that of the control group (P <0.05). The indications of patients in the observation group, rational medication time, reasonable route of administration, reasonable dosage, no combination therapy, the proportion of rational administration before surgery was higher than that of the control group (P <0.05). Conclusion Clinical pharmacists have a significant role in the prevention of antimicrobial agents in patients undergoing thoracic surgery perioperatively, which can effectively increase the rational use of antimicrobial agents, relieve the economic burden of patients, shorten the hospital stay and prompt the rapid recovery of the disease.