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甲状腺机能亢进患者血清总硷性磷酸酶(ALP)活性高于正常参考范围已有过报道。ALP 同工酶分析表明,总ALP 增高。有的仅来自患者的肝脏,有的则只来自骨,有时两者皆有。本文测定了未经治疗的甲亢患者血浆总ALP 和肝、骨、肠ALP,同时与已治疗的甲亢患者和献血员作了比较。并发现肝、骨ALP 活性与肝、骨疾病的其他生化指标相关。方法作者分别测定了63例未经治疗的甲亢患者(第1组),58例已治疗的甲亢患者(第2组)和100名献血员(对照组)的总ALP 和肠、肝、骨ALP
Hyperthyroidism serum total alkaline phosphatase (ALP) activity higher than the normal reference range has been reported. ALP isozymes analysis showed that total ALP increased. Some only come from the patient’s liver, while others are only from the bones, and sometimes both. This article measured the plasma total ALP and liver, bone, intestine ALP in untreated patients with hyperthyroidism and compared hyperthyroidism patients and blood donors who had been treated. And found that liver, bone ALP activity and liver, bone disease and other biochemical indicators. Methods The authors tested total ALP, intestinal, liver and bone ALP in 63 patients with untreated hyperthyroidism (group 1), 58 patients with hyperthyroidism (group 2) and 100 blood donors (control group)