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目的探讨经肝动脉化疗栓塞(TACE)联合CT引导射频消融(RFA)治疗肝尾状叶原发性肝癌的疗效及安全性。方法回顾性分析肝尾状叶原发性肝癌患者16例,均先行TACE治疗,再行CT引导下RFA治疗,随访患者的手术并发症、无瘤生存时间及总生存时间。结果 15例患者实现完全消融,完全消融率为93.75%(15/16)。完全消融患者的无瘤生存时间为19.35个月。16例患者的总生存时间为44.62个月,1、3、5年的总生存率分别为88.23%、66.65%及33.18%。结论 TACE联合RFA治疗肝尾状叶原发性肝癌安全、有效。
Objective To investigate the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with CT-guided radiofrequency ablation (RFA) in the treatment of primary hepatocellular carcinoma of the caudate lobe. Methods A retrospective analysis of 16 patients with primary hepatocellular carcinoma of the caudate lobe was performed with TACE before CT-guided RFA. The surgical complications, tumor-free survival and overall survival were followed up. Results 15 patients achieved complete ablation, the complete ablation rate was 93.75% (15/16). The complete tumor-free survival of patients with complete ablation was 19.35 months. The overall survival of 16 patients was 44.62 months. The overall survival rates at 1, 3 and 5 years were 88.23%, 66.65% and 33.18%, respectively. Conclusions TACE combined with RFA is safe and effective in the treatment of hepatocellular caudate lobe hepatocellular carcinoma.