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目的分析乐山市2006~2010年出生缺陷发生趋势及其高危因素,制定干预措施,降低出生缺陷发生率。方法按照《四川省出生缺陷监测方案》要求,对乐山市23所医疗保健机构出生缺陷进行监测,由县妇幼保健院收集汇总上报。结果出生缺陷总发生率9.81‰,5年来围产儿出生缺陷发生率历经波峰后稳步下降,差异有统计学意义;孕产妇20岁及35岁年龄组,出生缺陷率明显增高;男性与女性出生缺陷发生率差异无统计学意义;乐山市出生缺陷前6位是多指/趾、小耳/无耳、外耳其他畸形、唇裂并腭裂、唇裂、尿道下裂;产前诊断率12.26%;出生缺陷发生与遗传及孕前产前监测有一定关联。结论进一步加强育龄妇女及其家庭健康教育促进,增强“三级预防”体系功能,重视婚前孕前检查与产前筛查(诊断)工作,做到早预防、早诊断、早处置,以降低出生缺陷发生率,改善出生人口素质。
Objective To analyze the trend and risk factors of birth defects in Leshan from 2006 to 2010 and to make interventions to reduce the incidence of birth defects. Methods According to the requirements of “Birth Defects Monitoring Program in Sichuan Province”, the birth defects of 23 health care institutions in Leshan were monitored and collected by the county MCH. Results The total incidence of birth defects was 9. 81 ‰. The incidence of birth defects steadily decreased after the peak in 5 years, with significant difference; the incidence of birth defects was significantly higher in males aged 20 and 35 years; birth defects in males and females There was no significant difference in the incidence between the two groups. The first 6 birth defects in Leshan were multi-finger / toe, small ear / no ear, other malformations of the external ear, cleft lip and cleft palate, cleft lip and hypospadia; prenatal diagnosis rate was 12.26%; birth defects And genetic and prenatal monitoring of a certain relationship. Conclusions To further promote the health education of women of childbearing age and their families, enhance the function of the “three-level prevention” system, pay attention to prenatal screening and prenatal screening (diagnosis) work, and achieve early prevention, early diagnosis and early disposal to reduce Birth defects, improve the quality of the birth population.