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幼年特发性关节炎(juvenile idiopathic arthritis,JIA)是儿童期风湿免疫科常见疾病,以慢性关节滑膜炎为主要特征,疾病病情迁延,容易复发.患儿免疫系统处于反复炎症状态,长期服用糖皮质激素或免疫抑制剂等使患儿面临药物毒不良反应和依从性的问题.营养状况和营养素对慢性炎症性疾病的影响是近年来的研究热点,良好的营养状态、合理的膳食结构和足够微量营养素的摄入有助于控制炎症并调节免疫,对于降低疾病活动度和改善远期预后具有重要意义.该文主要综述营养状态、膳食模式和微量营养素对幼年特发性关节炎免疫调节作用的研究进展,为患儿合理的膳食摄入提供依据.“,”Juvenile idiopathic arthritis (JIA) is a common disease in pediatric rheumatology and immunology department,characterized with the repeated attack of chronic arthrosynovitis.Considering recurrent inflammatory in the disease progress,the long-term use of glucocorticoids or immunosuppreants may cause various side effects and compliance problems in patients.Nutritional status and nutrients play an important role in regulating immune function,the effects of dietary nutrition on chronic inflammatory diseases has become a research hotspot recently.Good nutritional status,reasonable dietary structure and adequate intake of micronutrients can decrease disease activity and improve the long-term outcome.This article summarizes the immunoregulatory effects of nutritional status,dietary patterns and micronutrients on JIA,providing basis for reasonable dietary intake of patients.