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目的分析2002—2014年甘肃省武威市凉州区结核病防治工作的实施效果,为今后结核病防治工作重点提供科学依据。方法收集2002—2014年凉州区结核病防治工作的各类报表及基础资料,分析凉州区结核病防治工作产生的成效;应用Epi Data 3.0建立数据库,采用Spss 13.0软件进行统计学分析。结果凉州区可疑肺结核病患者就诊率逐年提高,由因症就诊向转诊转变;免费诊治活动性肺结核病患者10 493例,新涂阳患者平均登记率达到31.32/10万,涂阳患者平均登记率达到35.95/10万,活动性患者平均登记率达到80.85/10万;自2005年以来,新涂阳(χ2=476.83)、复治涂阳(χ2=378.40)在活动性肺结核病患者中占比逐渐减少,差异有统计学意义(均P<0.05);新涂阳患者2个月末(χ2=100.55)、3个月末(χ2=114.03)痰菌阴转率逐年提高,差异有统计学意义(均P<0.05);新涂阳患者治愈率逐年提高,差异有统计学意义(χ2=59.46,P<0.05);初治涂阴患者治疗成功率逐年提高,差异有统计学意义(χ2=31.17,P<0.05);复治涂阳患者治疗失败率明显高于新涂阳患者,差异有统计学意义(χ2=88.66,P<0.05);涂阳患者死亡率明显高于涂阴患者,差异有统计学意义(χ2=41.97,P<0.05);涂阳患者治疗中断率明显高于涂阴患者,差异有统计学意义(χ2=4.01,P<0.05)。结论武威市凉州区结核病防治工作成效显著,但应及早预防耐多药肺结核病的发病和流行。
Objective To analyze the implementation effect of tuberculosis prevention and control in Liangzhou District of Wuwei City, Gansu Province from 2002 to 2014, and provide a scientific basis for future TB prevention and control work. Methods Various reports and basic information on tuberculosis prevention and control work in Liangzhou District from 2002 to 2014 were collected to analyze the effects of tuberculosis prevention and control work in Liangzhou District. Epi Data 3.0 was used to establish the database and the statistical analysis was carried out by using Spss 13.0 software. Results The visiting rate of suspicious tuberculosis patients in Liangzhou district increased year by year from 10 493 cases of patients with active pulmonary tuberculosis and 31.32 to 100 000 cases of fresh smear positive cases. The registration rate reached 35.95 / 100000, the average registration rate of active patients reached 80.85 / 100000; since 2005, the new smear positive (χ2 = 476.83), retreatment smear positive (χ2 = 378.40) in patients with active pulmonary tuberculosis (Χ2 = 100.55), and sputum negative conversion rate increased year by year at the end of 3 months (χ2 = 114.03), with statistical difference (all P <0.05) (Χ2 = 59.46, P <0.05). The successful treatment rate of patients with smear-negative patients increased year by year, the difference was statistically significant (χ2 = 59.46, P <0.05) = 31.17, P <0.05). The failure rate of treatment of smear-positive patients was significantly higher than that of new smear-positive patients (χ2 = 88.66, P <0.05) , The difference was statistically significant (χ2 = 41.97, P <0.05); treatment of patients with smear positive discontinuous rate was significantly higher than that of smear negative patients, the difference was statistically significant ( χ2 = 4.01, P <0.05). Conclusion The results of tuberculosis prevention and treatment in Liangzhou District of Wuwei City are remarkable, but the incidence and prevalence of MDR-TB should be prevented as soon as possible.