目的探讨米非司酮对中期妊娠利凡诺引产的影响。方法将孕16～28周自愿要求终止妊娠的健康妇女120例,随机分为对照组和研究组,对照组(A组)60例利凡诺羊膜腔注入法,研究组(B组)在羊膜腔内注射利凡诺的同时口服米非司酮,50mg每12小时1次,连用3次,总量150mg。结果研究组产程发动率高,总产程时间短,与对照组相比,差异有统计学意义。结论米非司酮配合利凡诺用于终止孕16～28周,方法安全,简便,有效率高,有利于产程进展,缩短引产时间,预防产后出血,具有临床意义。 Objective To investigate the effect of mifepristone on the induction of labor during the second trimester of pregnancy. Methods A total of 120 healthy pregnant women who volunteered for termination of pregnancy during the first 16-28 weeks of gestation were randomly divided into control group and study group. Group A (60 cases) Intravenous rivanol at the same time oral mifepristone, 50mg every 12 hours 1, once every 3 times, the total 150mg. Results The study group had a high incidence of labor-induced labor and short delivery time. Compared with the control group, the difference was statistically significant. Conclusion Mifepristone combined with rivanol for termination of pregnancy 16-28 weeks, the method is safe, simple and effective, is conducive to progress of labor, shorten the time of induction of labor, prevention of postpartum hemorrhage, with clinical significance.