手足口病(HFMD)一般预后良好,仅少数重症患儿可引起心肌炎、肺水肿和脑炎等并发症,病情进展迅速,导致死亡。2008年国家将手足口病纳入法定报告传染病管理,桂林市手足口病的报告病例数也逐年上升,并于2008年开始出现了死亡病例。对2012年报告的12例病例进行分析。1材料与方法 1.1资料来源12例死亡病例基本信息来源于国家传染病报告信息管理系统,由专业技术人员开展个案 Hand-foot-mouth disease (HFMD) generally has a good prognosis. Only a few critically ill children can cause complications such as myocarditis, pulmonary edema and encephalitis. The disease progresses rapidly and leads to death. In 2008, the state included hand-foot-mouth disease in the management of notifiable infectious diseases and the number of reported cases of hand-foot-mouth disease in Guilin also increased year by year. In 2008, deaths began to occur. 12 cases reported in 2012 were analyzed. 1 Materials and Methods 1.1 Sources 12 cases of deaths from the basic information of the national infectious disease reporting information management system, carried out by the case of professional and technical personnel