甲基丙二酸乙酯等烷基取代的丙二酸酯类是有机合成常用原料。实验室通常采用卤代烷和丙二酸酯反应制备,但往往含有同系物杂质。这些同系物用一般蒸馏或分馏方法很难分离干净,但可用气相色谱法顺利地进行分离和分析。 Alkyl-substituted malonic esters, such as ethyl methylmalonate, are common raw materials for organic synthesis. Laboratories usually use alkyl halides and malonate reactions, but often contain homologue impurities. These homologues are difficult to separate and clean by general distillation or fractionation methods, but can be successfully separated and analyzed by gas chromatography.