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目的探讨非特异性炎症因子超敏C-反应蛋白(hs-CRP)、纤维蛋白原(Fbg)和D-二聚体(D-Dime)水平与老年人急性心肌梗死(AMI)冠脉病变程度之间的关系。方法测定经选择性冠状动脉造影(CAG)证实为AMI患者(n=100)的hs-CRP、Fbg、D-Dime浓度,分析冠脉病变支数与相应hs-CRP、Fbg、D-Dime浓度的关系。结果非特异性炎症因子hs-CRP、Fbg和D-Dime浓度在单支病变组、双支病变组、三支病变组以及左主干组,其浓度依次增高。结论非特异性炎症因子水平与冠脉病变程度关联密切,有助于临床上预测老年人急性心肌梗死冠脉病变的范围。
Objective To investigate the relationship between the levels of hs-CRP, Fbg and D-Dime and the severity of coronary artery disease in elderly patients with acute myocardial infarction (AMI) Relationship between. Methods The concentrations of hs-CRP, Fbg and D-Dime in patients with AMI confirmed by selective coronary angiography (CAG) were measured. The number of coronary lesions and the corresponding hs-CRP, Fbg and D-Dime concentrations Relationship. Results The concentrations of hs-CRP, Fbg and D-Dime, which were nonspecific inflammatory factors, were significantly higher in the single vessel disease group, the double vessel disease group, the triple vessel disease group and the left main group. Conclusion The level of nonspecific inflammatory cytokines is closely related to the degree of coronary artery disease. It is helpful to predict the extent of coronary artery disease in elderly patients with acute myocardial infarction.