Among the macromolecular drug targets in neurodegenerative disorders, the neurotrophin brain-derived neurotrophic factor(BDNF) and its high-affinity tropomyosin
<正>Targeting early steps in amyloid-beta production:Alzheimer’s disease(AD)has a long history as the'amyloid deposit'disorder.Many disorders are now k
HECT, UBA and WWE domain-containing 1(Huwe1), an E3 ubiquitin ligase involved in the ubiquitin-proteasome system, is widely expressed in brain tissue. Huwe1 is