论文部分内容阅读
目的探讨血清脂联素(adiponectin)、血脂在肥胖儿及正常儿体内的变化情况及脂联素与体重指数(BMI)、体脂肪率(FATR)、血脂等相关关系。方法测定肥胖儿及正常儿各30例的血清脂联素、甘油三酯(TG)、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等,并进行两组之间的比较。结果肥胖儿组脂联素(10·06±4·87)mg/L明显低于正常对照组(13·18±5·18)mg/L,两者差异有显著性意义(P<0·05),肥胖儿组低密度脂蛋白胆固醇(3·10±1·08)mmol/L明显高于正常对照组(2·48±0·71)mmol/L,两者差异有显著性意义(P<0·05)。肥胖儿组甘油三酯(2·54±1·11)mmol/L明显高于正常对照组(1·75±0·79)mmol/L,两者差异有非常显著意义(P<0·01),肥胖儿组脂联素和体重指数BMI呈负相关(r=-0·53,P=0·00)。结论肥胖组较非肥胖对照组血中脂联素水平降低,血脂水平异常。
Objective To investigate the changes of serum adiponectin, blood lipids in obese children and normal infants and the relationship between adiponectin and body mass index (BMI), body fat percentage (FATR) and blood lipids. Methods Serum levels of adiponectin, triglyceride (TG), cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were measured in 30 obese children and normal children , And make a comparison between the two groups. Results The level of adiponectin (10 · 06 ± 4.87) mg / L in obese children was significantly lower than that of the control group (13 · 18 ± 5 · 18) mg / L, with significant difference (P <0 · 05). The LDL cholesterol (3.10 ± 1.08) mmol / L in obese children was significantly higher than that of the normal control group (2.48 ± 0.71 mmol / L), and the difference was significant P <0 · 05). The level of triglyceride (2. 54 ± 1 · 11) mmol / L in obese children was significantly higher than that of the control group (1.75 ± 0.79) mmol / L, with significant difference between the two groups (P <0.01 ), Adiponectin adiponectin and body mass index BMI was negatively correlated (r = -0.53, P = 0.00). Conclusion Compared with non-obese control group, adiponectin levels in obesity group are lower and blood lipid level is abnormal.