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目的探讨阿奇霉素联合克拉霉素治疗小儿支原体肺炎的疗效,为临床提供参考。方法选取90例小儿支原体肺炎的患者,随机分为对照组和治疗组,对照组给予阿奇霉素进行治疗,治疗组给予阿奇霉素联合克拉霉素进行治疗,比较两组患者经治疗后的临床疗效、主要生理指标复常时间及不良反应等。结果经治疗后,对照组总有效率为72.1%,治疗组为95.3%,治疗组与对照组比较差异有统计学意义(P<0.05);治疗组在体温复常时间、咳嗽消失时间、症状好转时间及住院时间较对照组差异有统计学意义(P<0.05);两组患者均未出现其他严重的不良反应。结论阿奇霉素联合克拉霉素用于治疗小儿支原体肺炎,可显著缩短生理指标复常时间,提高临床疗效,安全性较好,具有较大的临床借鉴意义。
Objective To investigate the curative effect of azithromycin combined with clarithromycin in treating children with mycoplasma pneumonia and provide reference for clinical practice. Methods Ninety cases of children with mycoplasma pneumonia were randomly divided into control group and treatment group. The control group was treated with azithromycin. The treatment group was treated with azithromycin combined with clarithromycin. The clinical efficacy, main physiology, Indicators of normal time and adverse reactions. Results After treatment, the total effective rate of the control group was 72.1%, the treatment group was 95.3%, the difference between the treatment group and the control group was statistically significant (P <0.05); the treatment group in the body temperature normal time, disappearance of cough, symptoms The improvement time and hospitalization time were significantly different from the control group (P <0.05). No other serious adverse reactions occurred in both groups. Conclusion Azithromycin combined with clarithromycin for the treatment of children with mycoplasma pneumonia, can significantly shorten the time of recovery of physiological indicators, improve clinical efficacy, safety is good, with great clinical significance.