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在临床研究中,已有人将乙基紫苏霉素或丁胺卡那霉素每日3次或2次(通常与一种或多种其他抗生素合用)与每日1次的治疗方法进行了比较。结果表明,两种治疗的疗效相同,并且每日1次治疗的毒性反应可能较低。尚无人对广泛用于临床的庆大霉素进行这一方面的试验。本文报道严重感染患者使用庆大霉素每日1次与每日3次两种治疗方法的疗效比较。
In clinical studies, ethyl musximin or amikacin has been administered once or twice daily (usually in combination with one or more other antibiotics) with once-daily treatments Compare The results showed that the two treatments had the same effect and the toxicity of once daily treatment was likely to be low. No one has done this aspect of gentamicin widely used in clinical trials. This article reports the use of gentamicin once daily and three times daily in patients with severe infections compared to two therapies.