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目的探讨癫癎患者认知功能障碍及其影响因素。方法采用韦氏儿童智力量表、成人智力量表对102例癫癎患者的认知功能进行评估,分析发病年龄、发作频率、发作时相、服用抗癫癎药物(AEDs)种类等因素对认知的影响。结果韦氏智力量表评估提示癫癎患者认知功能障碍发生率为82.2%。单因素差异分析显示发作频率、发作时相、单药治疗和多药治疗、服用AEDs种类均与认知功能损害程度相关。结论癫癎患者存在明显的认知功能障碍,发作频率、发作时相、AEDs服用情况均是影响癫癎患者认知功能的主要因素。
Objective To investigate the cognitive dysfunction and its influencing factors in patients with epilepsy. Methods The cognitive function of 102 patients with epilepsy was assessed by Wechsler Children Intelligence Scale and Adult Intelligence Scale. The age of onset, frequency of seizure, the onset of seizure and the type of antipsychotic drugs (AEDs) were analyzed. Know the impact. Results Wechsler’s assessment of intelligence scale prompted the incidence of cognitive impairment in patients with epilepsy was 82.2%. Univariate analysis of variance showed that seizure frequency, seizure phase, monotherapy and multi-drug therapy, taking AEDs species are associated with the degree of cognitive impairment. Conclusion There are obvious cognitive dysfunction in epilepsy patients. The frequency of seizure, the time of onset and the taking of AEDs are all the major factors that affect the cognitive function of epileptic patients.