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41BB是由Kwon等〔1〕于1989年在小鼠CD4+、CD8+T细胞中发现的一种膜表面分子,它在T淋巴细胞活化过程中发挥着协同刺激作用〔1〕。1996年Lotz等〔2〕分离出经淋巴细胞活化诱导的膜分子称为ILA(inducedbylymphocyt
4 1 BB is a membrane surface molecule found in mice CD4 +, CD8 + T cells by Kwon et al 〔1〕 in 1989, it plays a synergistic stimulus in the activation of T lymphocytes 〔1〕. In 1996, Lotz et al [2] isolated by lymphocyte activation induced membrane molecule called ILA (inducedbylymphocyt