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作者研究了cAMP在电针治疗大鼠和小鼠吗啡成瘾中的作用。给大鼠腹腔注射盐酸吗啡和小鼠埋植吗啡药丸使之成瘾。在动物耳部相当于人的“肺点”进针,以125 Hz、0.5～4 V电压进行电针60分钟。电针30分钟后,给实验鼠腹腔注射纳洛酮(大鼠0.2 mg/kg、小鼠10 mg/kg)引起撤药反应。一般在注射纳洛酮15分钟后出现身体颤抖、异常姿态、牙震、腹泻、跳跃、逃逸等撤药反应。在撤药反应出现15分钟后,维持电
The authors studied the role of cAMP in morphine addiction in rats and mice treated with electroacupuncture. Intraperitoneal injection of morphine hydrochloride in mice and implants of morphine in mice addicted. In the animal’s ear is equivalent to the human “lung point” into the needle, with 125 Hz, 0.5 ~ 4 V electro-acupuncture for 60 minutes. After 30 minutes of electroacupuncture, intraperitoneal injection of naloxone (0.2 mg / kg in rats and 10 mg / kg in mice) to the experimental mice resulted in the withdrawal response. General in the injection of naloxone 15 minutes after the occurrence of body trembling, abnormal posture, toothpaste, diarrhea, jumping, escape and other withdrawal reactions. 15 minutes after withdrawal reaction, maintain the electricity