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目的观察不同血清B型脑钠肽(BNP)浓度的甲状腺功能亢进性心脏病(HHD)患者左心功能指标变化。方法连续选择67例HHD患者,治疗前同时进行彩色多普勒超声检查和血清BNP测定。结果 67例HHD患者血清BNP水平为84~1 075(675.29±136.70)ng/L,高血清BNP组(BNP≥675.29 ng/L,31例)的LVESd和LVEDd值明显高于对照组(BNP<675.29 ng/L,36例),而SV、VCF和EF%等指标均明显低于后者(P均<0.05~0.01)。结论血清BNP浓度可明确影响HHD患者的左心功能指标。
Objective To observe the changes of left ventricular function in patients with hyperthyroidism (HHD) with different levels of serum BNP. Methods Sixty-seven patients with HHD were selected continuously, and color Doppler ultrasound and serum BNP were measured before treatment. Results The serum BNP level in 67 HHD patients was 84-1,075 (675.29 ± 136.70) ng / L, and LVESd and LVEDd values were significantly higher in BNP group (BNP> 675.29 ng / L, 31 cases) than those in control group (BNP < 675.29 ng / L, 36 cases), while the indexes of SV, VCF and EF% were significantly lower than those of the latter (all P <0.05-0.01). Conclusions Serum BNP concentration can clearly affect left ventricular function in patients with HHD.