论文部分内容阅读
目的观察阿托伐他汀治疗老年糖尿病患者伴血脂异常的疗效及安全性。方法选取2010年6月至2010年12月收治的2型糖尿病伴血脂异常患者60例。所有患者给予阿托伐他汀(辉瑞制药有限公司)10mg,睡前顿服,治疗8周。在治疗前及治疗8周后分别测定总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白胆固醇(HDL-C)及空腹血糖和餐后2h血糖,治疗8周后观察疗效。结果经过治疗,TC、TG、HDL-C、LDL-C水平与治疗前比较差异有统计学意义(P<0.05)。结论阿托伐他汀治疗老年糖尿病患者伴血脂异常疗效满意,无明显不良反应。
Objective To observe the efficacy and safety of atorvastatin in treating elderly patients with diabetes mellitus with dyslipidemia. Methods Sixty patients with type 2 diabetes mellitus and dyslipidemia who were admitted from June 2010 to December 2010 were selected. All patients were given atorvastatin (Pfizer Pharmaceutical Co., Ltd.) 10mg, Dayton clothing before going to bed for 8 weeks. Total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL-C), high density lipoprotein cholesterol (HDL-C) and fasting plasma glucose Blood sugar, after 8 weeks of treatment to observe the effect. Results After treatment, the levels of TC, TG, HDL-C and LDL-C were significantly different from those before treatment (P <0.05). Conclusions Atorvastatin is effective in treating senile diabetes patients with dyslipidemia without obvious adverse reactions.