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目的了解南宁市无偿献血大学生感染指标检测情况,为完善安全血液招募策略提供依据。方法采用酶联免疫吸附试验对2012—2016年6月南宁市参加无偿献血的103015名在校大学生乙肝表面抗原(HBsAg)、丙肝抗体(HCV抗体)、梅毒抗体(TP抗体)和人类免疫缺陷病毒抗体(HIV抗体)进行检测。结果103015名在校无偿献血大学生中,HBsAg,HCV抗体,TP抗体和HIV抗体阳性率分别为0.42%,0.23%,0.14%和0.13%,不同年份间HBsAg阳性率差异有统计学意义(χ~2=15.697,P=0.003),其余3种传染病标志物差异均无统计学意义(P值均>0.05)。在校大学生检测总阳性率、HBsAg和TP抗体阳性率均低于其他献血人群,但HCV抗体阳性率高于其他人群(χ~2值分别为1031.659,29.778,419.980,14.667,P值均<0.05);HIV抗体阳性率在两类人群间差异无统计学意义(χ~2=0.929,P=0.335)。结论南宁市在校大学生血液安全性的优势不明显。应加强在校大学生预防经血液传播疾病的宣传教育,以促进无偿献血事业的持续健康发展。
Objective To understand the detection of infectious indicators of college students who have not paid for blood donation in Nanning City, and provide the basis for improving the safe blood recruitment strategy. Methods Enzyme-linked immunosorbent assay (ELISA) was used to detect HBsAg, HCV antibody, syphilis antibody (TP antibody) and human immunodeficiency virus (HIV) in 103,015 college students participating in voluntary blood donation from 2012 to June 2016 in Nanning. Antibody (HIV antibody) test. Results The positive rates of HBsAg, HCV, TP and HIV were 0.42%, 0.23%, 0.14% and 0.13% among the 103,015 unpaid college students who donated blood. The positive rates of HBsAg in different years were significantly different (χ ~ 2 = 15.697, P = 0.003). There was no significant difference in the other three infectious disease markers (P> 0.05). The positive rates of HBsAg and TP antibody in college students were lower than those in other blood donors, but the positive rate of HCV antibody was higher than other groups (χ ~ 2 values were 1031.659, 29.778, 419.980 and 14.667, P <0.05 respectively) ). There was no significant difference in the positive rate of HIV antibody between the two groups (χ ~ 2 = 0.929, P = 0.335). Conclusion The advantage of blood safety of college students in Nanning is not obvious. Publicity and education on prevention of blood-borne diseases should be strengthened among undergraduates in order to promote the sustained and healthy development of the cause of unpaid blood donation.