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应用扫描镜超微病理技术,分析对比了肺癌患者胸膜间皮细胞与正常人胸膜间皮细胞间超微形态的异同。结果显示:正常成人胸膜脏层间皮细胞轮廓清楚,间皮细胞表面布满高低不一的微嵴及微绒毛。肺癌患者间皮细胞肿胀,细胞表面微嵴消失且出现大量细胞孔,浆膜游离面有大量渗液。依据扫描电镜所见,作者提出肺表面间皮细胞改变是肺癌导致胸水形成的形态学基础。
Ultrasound pathology of the scanning microscope was used to analyze and compare the ultrastructural similarities between pleural mesothelial cells and normal human pleural mesothelial cells. The results showed that the visceral mesothelial cells of normal adult viscera were well-defined and the surface of mesothelial cells was covered with high and low levels of microvulsions and microvilli. In patients with lung cancer, the mesothelial cells swelled, the cell surface disappeared and a large number of cell pores appeared, and there was a large amount of exudate on the free surface of the serosa. According to scanning electron microscopy, the authors propose that the change of mesothelial mesothelial cells is the morphological basis of pleural effusion caused by lung cancer.