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目的评价中西医结合治疗青少年高脂血症的临床疗效。方法选取86例确诊为青少年高脂血症患儿随机分为治疗组和对照组,对照组单纯给予阿托伐他汀10 mg/d,治疗组在对照组治疗的基础上口服四炒平脂汤,每日1剂,4周为1个疗程,1个疗程后观察2组患儿血脂水平变化。结果对照组显效18例(占41.9%),总有效率为72.1%;治疗组显效30例(占69.8%),总有效率93.1%。2组显效率和总有效率比较,差异均有统计意义(P<0.05)。同组患儿治疗后与治疗前比较,差异均有高度统计意义(P<0.01)。治疗后2组患儿的血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平比较,差异均有统计意义(P<0.05或P<0.01)。结论中西医结合治疗青少年高脂血症临床疗效满意。
Objective To evaluate the clinical efficacy of integrated traditional Chinese and western medicine in treating juvenile hyperlipidemia. Methods Totally 86 children diagnosed as adolescent hyperlipidemia were randomly divided into treatment group and control group, the control group was given atorvastatin 10 mg / d, the treatment group was treated with the control group, , 1 day, 4 weeks for a course of treatment, after a course of treatment observed in two groups of children with changes in blood lipid levels. Results The control group was markedly effective in 18 cases (41.9%), the total effective rate was 72.1%; the treatment group was markedly effective in 30 cases (69.8%), the total effective rate was 93.1%. The two groups were markedly effective and total effective rate, the difference was statistically significant (P <0.05). The same group of children after treatment compared with before treatment, the differences were highly statistically significant (P <0.01). After treatment, the levels of serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) (P <0.05 or P <0.01). Conclusion Integrative treatment of adolescent hyperlipidemia clinical efficacy satisfactory.