目的　探明湖南省SARS流行状况 ,分析SARS流行的影响因素 ,为进一步完善SARS防制策略提供科学的决策依据。　方法　应用ELISA方法检测病例及不同正常人群血清标本的SARS -CoVIgG抗体 ;采取回顾性调查研究方法 ,评价湖南省 2 0 0 3年采取的SARS干预措施。　结果　湖南省共发现 7例SARS -CoVIgG抗体阳性病例 ,均为传入性病例。密切接触人群和流行区返湘正常人群中分别检出 2例抗体阳性者 (病例从返乡到发现的时间间隔中位数为 0d ,发现到报告的时间间隔为 0h ,流调在报告后 1h内进行 ,隔离与报告同步 ,疫点的消毒率为 10 0 % ,密切接触者均被调查、医学观察 )。　结论　 2 0 0 3年全省发生了SARS的传入 ,但未出现续发病例 ,主要原因是湖南省党政高度重视 ,行动迅速 ,疫情监测报告灵敏 ,“四早”措施落实 ,疫情处理及时规范。已建立的早期症状监测预警系统 ,能及时发现鉴别可疑病例。 Objective To find out the epidemic situation of SARS in Hunan Province and analyze the influencing factors of SARS epidemic so as to provide scientific decision-making basis for further improving SARS prevention and control strategy. Methods Serological samples of SARS-CoV IgG antibodies were detected by ELISA in patients and different normal subjects. A retrospective survey was conducted to evaluate the SARS interventions taken in Hunan Province in 2003. Results A total of 7 SARS-CoVIgG antibody positive cases were found in Hunan Province, all of which were invasive cases. Closely contacted with the crowd and epidemic areas returned to normal Hunan were detected in 2 cases of antibody positive (cases from the return to the discovery of the median time interval was 0d, found to report the time interval 0h, flow control in the report after 1h The isolation and reporting were synchronized. The disinfection rate of the epidemic was 10%. Close contacts were investigated and medical observation was conducted. Conclusions In 2003, there were SARS cases in the province, but no cases of recurrence occurred. The main reason was that Hunan’s party and government attached great importance to the disease and acted promptly. The reports of epidemic situation were sensitive. Measures of “four early mornings” were implemented and outbreaks were handled promptly specification. Has established early warning system for early detection of symptoms, timely identification of suspected cases of doubt.