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目的探讨行机械通气的婴幼儿重症肺炎的患儿,监测呼气末二氧化碳分压(PetCO2)与动脉血二氧化碳分压(PaCO2)的相关性。方法采取回顾性、自身对照研究方法。选择32例进行机械通气的婴幼儿重症肺炎患儿,在机械通气后同时检测呼气末二氧化碳分压(PetCO2)和动脉血二氧化碳分压(PaCO2)。分别选择机械通气后30min、1h、6h、12h、24h,5个时间点进行检测。结果呼气末二氧化碳分压(PetCO2)和动脉血二氧化碳分压(PaCO2)具有正向关关系(r=0.8210,P<0.0001)。结论进行机械通气的婴幼儿重症肺炎,呼气末二氧化碳分压(PetCO2)和动脉血二氧化碳分压(PaCO2)具有很好的相关性,呼气末二氧化碳分压(PetCO2)可用于判断动脉血二氧化碳分压(PaCO2)变化,可以作为调整呼吸机参数的依据,减少动脉采血痛苦,值得临床推广。
Objective To investigate the relationship between end-tidal carbon dioxide (PetCO2) and arterial carbon dioxide (PaCO2) in children with severe pneumonia undergoing mechanical ventilation. Methods A retrospective, self-controlled study was conducted. Thirty-two infants with severe pneumonia were selected for mechanical ventilation. PetCO2 and PaCO2 were measured simultaneously after mechanical ventilation. Mechanical ventilation were selected 30min, 1h, 6h, 12h, 24h, 5 time points for testing. Results There was a positive correlation between PetCO2 and PaCO2 (r = 0.8210, P <0.0001). Conclusions There is a good correlation between PetCO2 and PaCO2 in mechanically ventilated severe pneumonia in infants and young children. The end-tidal carbon dioxide partial pressure (PetCO2) can be used to determine arterial carbon dioxide Partial pressure (PaCO2) changes, can be used as a basis for adjusting the ventilator parameters to reduce arterial blood pain, worthy of clinical promotion.