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对５０例接受托槽直接粘接技术做口腔错牙合畸形矫治后患者的牙采由质酸蚀区表面，采用含氟和不含氟牙膏处理方法做了比较研究。随访治疗６个月时，用含氟牙膏处理组８８．５％的患者酸蚀牙采由质面完全恢复，其余的患者也接近正常，而用不含氟牙膏的对照组，９１．７％的患者酸蚀牙采由质面无变化。结果：氟化物牙膏对于因正畸需要而做酸处理的牙齿表面有明显的防脱矿作用。
50 patients received brackets direct bonding technique to do oral malocclusion orthodontic treatment of teeth taken from the surface of the acid etching zone, the use of fluoride and fluoride-free toothpaste treatment methods were compared. Follow-up treatment for 6 months, 88.5% of patients treated with fluoride toothpaste acid etching teeth fully recovered by the surface, and the rest of the patients are close to normal, but with fluoride-free toothpaste control group, 91.7% The patient's teeth eroded by the face no change. Results: Fluoride toothpaste has a significant anti-demineralization effect on the surface of the tooth treated with acid for the purpose of orthodontic treatment.