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目的:了解扬州地区已婚妇女宫颈上皮内瘤变(C IN)的患病情况,为制定干预措施提供依据。方法:采用横断面调查方法,于2009年3月至2009年12月,对扬州广陵区户籍的25~65岁已婚妇女13 000例采用宫颈刷行宫颈刮片检查,巴氏染色,采用TBS细胞学诊断标准;并对宫颈刮片有异常者行阴道镜下宫颈活组织检查。结果:13 000例妇女中,宫颈刮片异常者占6.13%(797/13 000);阴道镜下宫颈活组织检查757例,诊断为C IN者占3.75%(487/13000),占宫颈刮片结果异常者的64.33%(487/797),其中C INⅠ为1.72%(223/13 000),C INⅡ为1.11%(144/13 000),C INⅢ为0.92%(120/13 000);早期浸润癌0.02%(2/13 000)。结论:扬州地区已婚妇女C IN的患病率为3.75%,早期对C IN干预和治疗可有效降低宫颈癌的发生率。
Objective: To understand the prevalence of cervical intraepithelial neoplasia (CIN) in married women in Yangzhou and to provide evidence for the development of interventions. Methods: From March 2009 to December 2009, 13 000 married women aged 25-65 with household registration in Guangling district of Yangzhou were examined by cervical smear and Pap smear with TBS Cytology diagnostic criteria; and cervical smear abnormalities underwent colposcopic cervical biopsy. Results: Out of 13 000 women, cervical smear abnormalities accounted for 6.13% (797/13 000); colposcopic cervical biopsy 757 cases, diagnosed as C IN accounted for 3.75% (487/13000), accounting for cervical scraping The results showed that 64.33% (487/797) of the patients with abnormal result showed that the C IN Ⅰ was 1.72% (223/13 000), the C IN Ⅱ was 1.11% (144/13 000) and the C IN Ⅲ was 0.92% (120/13 000). Early invasive cancer 0.02% (2/13 000). Conclusion: The prevalence of C IN in married women in Yangzhou is 3.75%. Early intervention and treatment with C IN can effectively reduce the incidence of cervical cancer.