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首次产检在孕>6≤14周发现FPG异常者,给予饮食运动干预。再根据孕18周前馒头餐试验及孕24周前OGTT试验结果,分为(normal glucose tolerance)NGT、(gestational impaired glucose tolerance)GIGT、(gestational diabetes)GDM三组,进行综合干预后,随访统计产后风险及不良结局的差异。结果:NGT242例、GIGT组91例、GDM组例31例,NGT组与组GIGT组比较早产儿、巨大儿、产伤、剖宫产有差异P<0.01。NGT组与GDM组比较在早产、巨大儿、新生儿低血糖、高胆红素血症、妊高症、产伤、剖宫产有差异P<0.05。GIGT组与GDM组比较巨大儿、新生儿低血糖、高胆红素血症、妊高症、产伤、剖宫产有差异P<0.05。结论:妊娠早期即孕>6≤14周进行FPG检查是必要的,早期发现的妊娠血糖异常,较NGT人群产后风险高、不良结局广泛。建议在有条件的情况下妊娠早期首次产检时即孕>6≤14周进行FPG检查,可进一步保障母婴良好结局。
The first childbirth in pregnant> 6 ≤ 14 weeks found FPG abnormalities, to give dietary exercise intervention. According to the results of steamed bread test 18 weeks before pregnancy and the results of OGTT 24 weeks before pregnancy, the patients were divided into three groups: normal glucose tolerance (NGT), gestational impaired glucose tolerance (GIGT) and gestational diabetes (GDM) Differences in postpartum risk and adverse outcomes. Results: There were 242 NGT cases, 91 GIGT cases and 31 GDM cases. There was significant difference between NGT group and GIGT group in preterm children, giant children, birth trauma and cesarean section. NGT group and GDM group in preterm labor, macrosomia, neonatal hypoglycemia, hyperbilirubinemia, pregnancy-induced hypertension, birth trauma, cesarean section difference P <0.05. GIGT group and GDM group compared with giant children, neonatal hypoglycemia, hyperbilirubinemia, pregnancy-induced hypertension, birth trauma, cesarean section differences P <0.05. Conclusion: It is necessary to carry out FPG examination in the first trimester, ie pregnancy> 6≤14 weeks. The early detection of abnormal glucose level in pregnancy is higher than the risk of postpartum in NGT population, and the adverse outcomes are extensive. It is recommended under the conditions of pregnancy in the first trimester of pregnancy when pregnancy> 6 ≤ 14 weeks for FPG examination, can further protect the mother and child good outcome.