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随机抽样414名镍钴作业人员与100名非镍钴作业人员进行对照研究。镍钴作业组空气中镍钴污染比对照组分别高2．7－18．0倍和3．7－11．1倍。镍钴作业者尿液中镍结合量和头发中镍钴含量均比对照明显增高，差异有非常显著性（P＜0．01）。镍钴作业组与对照组年龄组分布相同无差异。晶体检查参照Chylack的IDCSⅠ、Ⅱ标准，镍钴作业组晶体混浊的检出率（53．5％）明显高于对照组（17．0％）、P＜0．01镍钴对晶体的损伤是缓慢的过程。
A random sample of 414 nickel-cobalt workers was compared with 100 non-nickel-cobalt workers. Nickel-cobalt pollution in the nickel-cobalt operation group was 2.7-18.0 times higher and 3.7-11.1 times higher than that in the control group. Nickel-cobalt operators’ urinary nickel binding and nickel-cobalt content in hair were significantly higher than those in the control, and the difference was significant (P<0.01). There was no difference in the distribution of the nickel-cobalt operation group and the control group age group. According to Chyckard’s IDCSI and II standards, the detection rate of crystal turbidity in the nickel-cobalt operation group (53.5%) was significantly higher than that in the control group (17.0%). P<0.01 nickel-cobalt crystal damage was Slow process.