几乎所有药物均能由母体血浆进入乳汁,使乳儿无意之中成为用药者,这就使授乳中的母亲用药时必须考虑其移行至乳汁及其对乳儿的影响。药物在乳汁中的排泄不仅与剂量和疗程有关,而且与药物的结构、分子量、解离度、pH值、蛋白结合率、脂溶性以及给药 Almost all medications can enter the milk from maternal plasma, leaving unintentional use of the baby as a medication, making it imprudent for lactating mothers to consider their migration to the milk and their effects on the baby. Excretion of the drug in milk is not only related to the dosage and course of treatment, but also to the structure, molecular weight, dissociation, pH, protein binding, liposolubility, and administration of the drug