目前应用的丙酮杀死、干燥伤寒菌苗(AKD)接种后的全身反应有发热、肌痛、头痛和不适。在第三世界一些国家中试角AKD菌苗出现了流感样症候群。本文报道接种伤寒菌苗后的全身反应发生率和这些反应对实验室参数的影响。调查反应采用“双重法”,即在接种同时给接种者一份反应调查表,内容包括年龄、性别、免疫接种情况、既往沙门氏菌病史以及接种后发生的症状、持续时间等。此外,对所有发生反应而到急诊室就诊的病人都进行复查,并作实验室检查。特别注意重要体征、局部反应和局部淋巴结肿 The current use of acetone killed, dry septicemia vaccine (AKD) systemic disease after vaccination fever, muscle pain, headache and discomfort. In some countries in the Third World, flu-like symptoms were found in AKD vaccines. This article reports the incidence of systemic reactions after vaccination against typhoid bacteria and the effects of these reactions on laboratory parameters. The survey used a “dual approach,” in which vaccination was given to a responder with a response questionnaire that included age, sex, immunization status, previous salmonella histories and symptoms, duration, and the like after vaccination. In addition, all patients who responded to the emergency room were reviewed and lab tested. Special attention to important signs, local reactions and local lymph nodes