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生长激素分泌促进剂是一类作用于垂体和下丘脑的具有专一性促生长激素释放作用的寡肽及其类似物.由于其分子质量小、活性高、可口服、作用专一而有可能成为新的生长激素治疗药物.目前已经发展了很多具有此类活性的多种结构的化合物,如肽、环肽、肽醇及非肽类似物等.尽管这类化合物的作用机制尚未完全明确,但已有证据表明存在新的调节生长激素分泌的途径和新的调节因子.
Growth hormone secretion enhancers are a class of oligopeptides and their analogs that act on the pituitary and hypothalamus with a specific release of somatotropin. Due to its small molecular mass, high activity, can be oral, the role of specificity and may become the new growth hormone treatment of drugs. A large number of compounds with various structures such as peptides, cyclic peptides, peptide alcohols and non-peptide analogues have been developed. Although the mechanism of action of these compounds is not yet fully understood, there is evidence that there are new ways to regulate the secretion of growth hormone and new regulatory factors.