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[目的]了解长期住院精神分裂症患者并发糖尿病的相关因素。[方法]回顾性调查符合CCMD-3诊断标准的住院精神分裂症患者中的糖尿病发病情况以及抗精神病药物的使用情况等相关因素,并观察体重、血糖的变化。[结果]在172例长期住院的精神分裂症患者中,并发糖尿病者为21例(12.21%),其发生与患者的年龄、病程、体重和阳性糖尿病家族史以及使用抗精神病药物有相关性。[结论]精神分裂症患者中糖尿病的发生率远高于普通人群,年龄较大、病程较长以及抗精神病药物的长期使用均可增加糖尿病的发生率。
[Objective] To understand the related factors of long-term inpatients with schizophrenia complicated with diabetes. [Methods] The incidence of diabetes mellitus and the use of antipsychotic drugs in inpatients with schizophrenia conformed to the CCMD-3 diagnostic criteria were retrospectively investigated. The changes of body weight and blood glucose were observed. [Results] Among 172 long-term hospitalized schizophrenia patients, 21 (12.21%) had diabetes mellitus, which was related to the patient’s age, duration, weight, positive family history of diabetes and the use of antipsychotics. [Conclusion] The incidence of diabetes in schizophrenic patients is much higher than that in the general population. Older persons, longer duration of treatment and prolonged use of antipsychotics may increase the incidence of diabetes mellitus.