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本文观察良性前列腺增生 (BPH)中的高度前列腺上皮内瘤 (HPIN)现象。回顾性分析 5 4例行耻骨上前列腺摘除术患者的前列腺标本切片。统计其中HPIN的发生率 ,并结合患者术前血PSA值 ,分析HPIN与非HPIN之间的血PSA值差别。结果发现 5 4例患者中 2 2例有HPIN表现 ,占总数的 40 .7%。HPIN组与非HPIN组之间的血PSA值无显著性差异。在本组BPH患者中 ,HPIN表现占有一定比例 ,因此认为HPIN现象并非前列腺癌 (Pca)专有。本组中HPIN比例偏高与患者平均年龄较大有关。本研究通过血PSA测定尚无法简单区分HPIN和非HPIN。对于HPIN现象 ,一方面应提高警惕 ,密切随访 ;另一方面也不必盲目悲观 ,毕竟HPIN只是一种前列腺癌的前驱表现 ,而并不等同于前列腺癌
This article observes the phenomenon of high Prostatic intraepithelial neoplasia (HPIN) in benign prostatic hyperplasia (BPH). A retrospective analysis of 5 4 patients with suprapubic prostatectomy in patients with prostate specimens section. Statistics of the incidence of HPIN, and combined with preoperative blood PSA values, analysis of HPIN and non-HPIN blood PSA value differences. Results showed that 22 of 54 patients had HPIN, accounting for 40.7% of the total. There was no significant difference in serum PSA between HPIN and non-HPIN groups. In this group of patients with BPH, HPIN performance of a certain percentage, so that HPIN phenomenon is not prostate cancer (Pca) proprietary. The high proportion of HPIN in this group is related to the larger average age of patients. The study by blood PSA measurement can not be a simple distinction between HPIN and non-HPIN. On the HPIN phenomenon, on the one hand should be vigilant, close follow-up; the other hand do not have to blindly pessimistic, after all, HPIN is only a precursor of prostate cancer, but not the same as prostate cancer