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卵黄囊瘤是婴儿和儿童最常见的睾丸恶性肿瘤,约占总数的72％,多在12—24月时确诊。经腹股沟途径作根治性睾丸切除已成定论,但对嗣后要否作腹膜后淋巴清扫、放疗及化疗仍有争论。作者回顾了宾州儿童医院1971—1983年间11例典型睾丸卵黄囊瘤的治疗经验。肿瘤均为单侧,全属一期(肿瘤限于睾丸内)。经腹股沟途径作根治性睾丸切除后,4例加作腹膜后淋巴清扫术(均未发现有淋巴转移),部分患者辅以各种方案的联合化疗。结果:单作睾丸切除的4例中3例无癌生存已4.5、2.7和1.5年,1例术后
Yolk sac tumors are the most common testicular malignancy in infants and children, accounting for about 72% of the total number, and are mostly diagnosed at 12-24 months. The radical resection of the orchiectomy by the groin approach has already been definitive, but there is still controversy about whether retroperitoneal lymph node dissection, radiotherapy, and chemotherapy should be performed after the fistula. The authors reviewed the experience of treatment of 11 cases of typical testicular yolk sac tumors in Children’s Hospital of Pennsylvania from 1971 to 1983. The tumors are unilateral and all belong to the first phase (the tumor is limited to the testis). After radical orchiectomy by the inguinal approach, 4 cases were retroperitoneal lymphadenectomy (no lymph node metastasis was found), and some patients were supplemented with various regimens of combination chemotherapy. RESULTS: Of the 4 patients who underwent single testicular resection, 3 had no cancer survival of 4.5, 2.7 and 1.5 years, and 1 patient had postoperative