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目的：探讨EB病毒感染在间质性肾炎发病中的作用。方法：用PCR及原位杂交法对12例间质性肾炎及10例微小病变肾病患者的肾穿刺组织行EB病毒检测。结果：在间质性肾炎患者肾组织中存在较高的EB病毒阳性率。结论：EB病毒感染与间质性肾炎的发病有密切的联系，在不同类型的间质性肾炎中EB病毒感染可能有不尽相同的作用。
Objective: To explore the role of Epstein-Barr virus infection in the pathogenesis of interstitial nephritis. Methods: Epstein-Barr virus (EBV) was detected in renal biopsy tissues of 12 patients with interstitial nephritis and 10 patients with minimal change nephropathy by PCR and in situ hybridization. Results: There was a high positive rate of Epstein-Barr virus in renal tissue of patients with interstitial nephritis. Conclusion: Epstein-Barr virus infection is closely related to the pathogenesis of interstitial nephritis. Epstein-Barr virus infection in different types of interstitial nephritis may have different effects.