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应用分型McAb对陕西疫区分离的31株HFRSV进行抗原性比较,结果表明该疫区病人中主要为野鼠型病毒流行,但从个别病人来源的毒株McAb反应谱类似家鼠型,并有野鼠家鼠混合型毒株出现。提示同一流行疫区有可能存在不同型别的HFRSV。这对确定HFRSV的血清型及疫苗研制均有意义。。
The antigenicity of 31 HFRSV strains isolated in Shaanxi province was compared by typing McAb. The results showed that the prevalence of wild-type virus in this epidemic area was quite similar. However, the McAb response spectrum of individual strains was similar to that of domestic mice. Vermilion mixed strains appear. Suggesting that there may be different types of HFRSV in the same endemic area. This is of great significance in determining the serotype and vaccine development of HFRSV. .